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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of fungal keratitis
ncRNA name hsa-miR-511-5p
ncRNA Category miRNA
Disease name fungal keratitis
Species Homo sapiens
Tissues/Cell_line corneas
Methods RNA-seq, qRT-PCR
Expression pattern up-regulated
Functional description By deep sequencing, 75 miRNAs were identified as differentially expressed in fungal keratitis corneas. Based on high DE (≥6-fold) and functional relevance to corneal diseases, 16 miRNAs were selected for further validation by qPCR. The highly dysregulated miRNAs (miR-511-5p, miR-142-3p, miR-155-5p, and miR-451a) may regulate wound healing as they were predicted to specifically target wound inflammatory genes.
PubMed ID 26720440
Year 2015
Title Human Corneal MicroRNA Expression Profile in Fungal Keratitis.
Drug-related ncRNA NO

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